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Article

Characteristics and response to next-generation sequencing-guided therapy in locally advanced or metastatic esophageal cancer.

International journal of cancer - 1 Feb 2023

Ma Yueyun, Li Wenjie, Chen Shiyu, Lin Shuimiao, Ding Sijie, Zhou Xiaomei, Liu Tongxin, Wang Rong, Wang Wei

Abstract excerpt

Esophageal cancer (EC) is a main cause of cancer-related deaths. However, genomic alterations and the clinical value of next-generation sequencing (NGS) in advanced or metastatic EC for precision therapy remain largely unclear. Herein, we performed comprehensive analyses on a cohort of 47 individuals with advanced or metastatic EC who underwent NGS between May 2017 and February 2020. Eventually, 227 mutated genes...

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Identifiers

PMID: 36214796
DOI: 10.1002/ijc.34315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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