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Article

LACC1 polymorphisms in inflammatory bowel disease and juvenile idiopathic arthritis.

Genes and immunity - 1 Jun 2016

Assadi G, Saleh R, Hadizadeh F, Vesterlund L, Bonfiglio F, Halfvarson J, Törkvist L, Eriksson A S, Harris H E, Sundberg E, D'Amato M

Abstract excerpt

The function of the Laccase domain-containing 1 (LACC1) gene is unknown, but genetic variation at this locus has been reported to consistently affect the risk of Crohn's disease (CD) and leprosy. Recently, a LACC1 missense mutation was found in patients suffering from monogenic forms of CD, but also systemic juvenile idiopathic arthritis. We tested the hypothesis that LACC1 single nucleotide polymorphisms (SNPs),...

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Share to Arthritis, Juvenile
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

Share to Immunodeficiency and Autoimmune Disorders

Share to Intracellular Signaling Peptides and Proteins

Share to Mutation, Missense

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 27098602
DOI: 10.1038/gene.2016.17

Genes

LACC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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