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Article

LACC1 deficiency leading to juvenile arthritis and anemia.

Clinical immunology (Orlando, Fla.) - 1 Aug 2024

He Tingyan, Wang Linlin, Huang Xiaomei, Weng Ruohang, Yang Jun

Abstract excerpt

OBJECTIVE: Juvenile arthritis caused by loss-of-function LACC1 mutations is characterized by early onset of symmetric and chronic arthritis, associated with an elevation of inflammatory markers. We aimed to describe serum cytokine levels, explore the type I interferon pathway, and evaluate the efficacy of treatment in a patient presenting with polyarthritis and anemia caused by novel compound heterozygous...

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Source

Identifiers

PMID: 38944365
DOI: 10.1016/j.clim.2024.110290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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