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Article

Juvenile arthritis caused by a novel FAMIN (LACC1) mutation in two children with systemic and extended oligoarticular course.

Pediatric rheumatology online journal - 24 Nov 2016

Kallinich Tilmann, Thorwarth Anne, von Stuckrad Sae-Lim, Rösen-Wolff Angela, Luksch Hella, Hundsdoerfer Patrick, Minden Kirsten, Krawitz Peter

Abstract excerpt

BACKGROUND: The pathophysiological origin of juvenile idiopathic arthritis (JIA) is largely unknown. However, individuals with presumably pathogenic mutations in FAMIN have been reported, associating this gene with a rare subtype of this disorder. FAMIN, that is formerly also referred to as LACC1 or C13orf31, has recently been shown to play a crucial role in immune-metabolic functions and is involved in...

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Identifiers

PMID: 27881174
DOI: 10.1186/s12969-016-0124-2
PMCID: PMC5122026

Genes

LACC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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