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Article

Prognostic and predictive value of extended RAS mutation and mismatch repair status in stage III colorectal cancer.

Cancer science - 1 Jul 2016

Sasaki Yusuke, Akasu Takayuki, Saito Norio, Kojima Hiroshi, Matsuda Keiji, Nakamori Shoji, Komori Koji, Amagai Kenji, Yamaguchi Tatsuro, Ohue Masayuki, Nagashima Kengo, Yamada Yasuhide

Abstract excerpt

The prognostic and predictive value of KRAS gene mutations in stage III colorectal cancer is controversial because many recent clinical trials have not involved a surgery-alone arm. Additionally, data on the significance of extended RAS (KRAS/NRAS) mutations in stage III cancer are not available. Hence, we undertook a combined analysis of two phase III randomized trials, in which the usefulness of adjuvant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27089049
DOI: 10.1111/cas.12950
PMCID: PMC4946717

Genes

KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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