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Article

Lipolysis and lipophagy in lipid storage myopathies

13 Apr 2016

Abstract excerpt

AIMS: Triglycerides droplets are massively stored in muscle in Lipid Storage Myopathies (LSM). We studied in muscle regulators of lipophagy, the expression of the transcription factor-EB (TFEB) (a master regulator of lysosomal biogenesis), and markers of autophagy which are induced by starvation and exert a transcriptional control on lipid catabolism. METHODS: We investigated the factors that regulate lipophagy...

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PMID: 27085974
DOI: 10.1016/j.bbadis.2016.04.008

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