Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histological and molecular features of lipomatous and nonlipomatous adipose tissue in familial partial lipodystrophy caused by LMNA mutations.

Clinical endocrinology - 1 Jun 2012

Araújo-Vilar D, Victoria B, González-Méndez B, Barreiro F, Fernández-Rodríguez B, Cereijo R, Gallego-Escuredo J M, Villarroya F, Pañeda-Menéndez A

Abstract excerpt

OBJECTIVES: Type 2 familial partial lipodystrophy (FPLD2) is a rare adipose tissue (AT) disease caused by mutations in LMNA, in which lipomas appear occasionally. In this study, we aimed to histologically characterize FPLD2-associated lipomatosis and study the expression of genes and proteins involved in cell cycle control, mitochondrial function, inflammation and adipogenesis. DESIGN AND PATIENTS: One lipoma and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CCAAT-Enhancer-Binding Protein-beta

Share to In Vitro Techniques

Share to Lamin Type A

Share to Lipodystrophy, Familial Partial

Share to Real-Time Polymerase Chain Reaction

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 21883346
DOI: 10.1111/j.1365-2265.2011.04208.x

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histological and molecular features of lipomatous and nonlipomatous adipose tissue in familial partial lipodystrophy caused by LMNA mutations.PMID 21883346Read ↗

A Rare Mutation in LMNB2 Associated with Lipodystrophy Drives Premature Cell Senescence.Semantic proximity Read ↗

A recurrent familial partial lipodystrophy due to a monoallelic or biallelic LMNA founder variant highlights the multifaceted cardiac manifestations of metabolic laminopathies.Semantic proximity Read ↗

Deciphering the Clinical Presentations in LMNA-related Lipodystrophy: Report of 115 Cases and a Systematic Review.Semantic proximity Read ↗

The Clinical Characteristics and Potential Molecular Mechanism of LMNA Mutation-Related Lipodystrophy.Semantic proximity Read ↗

MFN2-associated lipomatosis: Clinical spectrum and impact on adipose tissueSemantic proximity Read ↗

Novel LMNA mutations seen in patients with familial partial lipodystrophy subtype 2 (FPLD2; MIM 151660).Semantic proximity Read ↗

Advances in lipodystrophy syndrome caused by LMNA gene mutation.Semantic proximity Read ↗

LMNA p.R482W mutation related to FPLD2 alters SREBP1-A type lamin interactions in human fibroblasts and adipose stem cellsSemantic proximity Read ↗

Familial Generalized and Partial Lipodystrophies Due to Rare Biallelic Variants in LMNA.Semantic proximity Read ↗

Mutational profiling of lipomasSemantic proximity Read ↗

Genetic Basis of Lipodystrophies and Management of Metabolic ComplicationsSemantic proximity Read ↗

LIPE-related lipodystrophic syndrome: clinical features and disease modeling using adipose stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.