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Article

Identification of Damaging nsSNVs in HumanERCC2 Gene.

Chemical biology & drug design - 1 Sept 2016

Fang Shuo, Zhang Yuntong, Xu Miao, Xue Chunyu, He Lin, Cai Lei, Xing Xin

Abstract excerpt

The hERCC2 gene is an important DNA repair molecule for initiating Cutaneous melanoma (CM). Therefore, it is advisable to study the possible functional SNVs in hERCC2. To achieve this goal, we collected total 2, 253 SNVs in hERCC2from the EMBL website, of which 303 are non-synonymous single nucleotide variants (nsSNVs). Then, SIFT and PolyPhen were used to predict the damaging nsSNVs, and four nsSNVs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27085493
DOI: 10.1111/cbdd.12772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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