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Article

Hedgehog gene polymorphisms are associated with the risk of Hirschsprung's disease and anorectal malformation in a Chinese population.

Molecular medicine reports - 1 Jun 2016

Gao Hong, Wang Dajia, Bai Yuzuo, Zhang Juan, Wu Mei, Mi Jie, Jia Huimin, Wang Weilin

Abstract excerpt

Hedgehog (HH) is one of the key morphogens expressed in the gut mesenchyme that control animal development and tissue homeostasis. The HH gene has been shown to be closely associated with Hirschsprung's disease (HSCR) and anorectal malformations (ARMs); thus, it was hypothesized that HH signaling pathway‑associated genes may be candidate genes for HSCR and ARMs. The present study aimed to evaluate whether...

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Identifiers

PMID: 27082974
DOI: 10.3892/mmr.2016.5139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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