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Article

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate.

Oncotarget - 10 May 2016

Gansmo Liv B, Vatten Lars, Romundstad Pål, Hveem Kristian, Ryan Bríd M, Harris Curtis C, Knappskog Stian, Lønning Per E

Abstract excerpt

The MDM2 promoter region contains several polymorphisms, some of which have been associated with MDM2 expression, cancer risk and age at cancer onset. del1518 (rs3730485) is an indel polymorphism residing in the MDM2 promoter P1 and is in almost complete linkage disequilibrium with the MDM2 promoter P2 polymorphism SNP309T>G (rs2279744). Cancer risk assessments of del1518 have previously been conducted in...

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Identifiers

PMID: 27081698
DOI: 10.18632/oncotarget.8705
PMCID: PMC5053751

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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