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Article

Association of the Del1518 Promoter (rs3730485) Polymorphism in the MDM2 Gene with Breast Cancer in a Mexican Population.

Annals of clinical and laboratory science - 1 May 2017

Gallegos-Arreola Martha Patricia, Márquez-Rosales María Guadalupe, Sánchez-Corona José, Figuera Luis Eduardo, Zúñiga-González Guillermo, Puebla-Pérez Ana María, Delgado-Saucedo Jorge Iván, Montoya-Fuentes Héctor

Abstract excerpt

INTRODUCTION: The MDM2 gene plays an important role in tumorigenesis. The data on the Del1518 promoter polymorphism in the MDM2 gene have revealed associations with cancer. MATERIAL AND METHODS: We examined the role of the MDM2 Del1518 polymorphism through a comparison of the genotypes of 345 healthy Mexican women with those of 742 Mexican women with breast cancer (BC). RESULTS: The genotype frequencies of the...

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Identifiers

PMID: 28667029

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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