Article
Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle.
BMC genomics - 9 Jan 2018
Peripolli Elisa, Stafuzza Nedenia Bonvino, Munari Danísio Prado, Lima André Luís Ferreira, Irgang Renato, Machado Marco Antonio, Panetto João Cláudio do Carmo, Ventura Ricardo Vieira, Baldi Fernando, da Silva Marcos Vinícius Gualberto Barbosa
Abstract excerpt
BACKGROUND: Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i) to investigate genome-wide autozygosity to identify and characterize ROH patterns in Gyr dairy cattle genome; (ii) identify ROH islands for gene content and...
Topics
- Animals
- Cattle
- Female
- Genomics
- Homozygote
- Inbreeding
- Lactation
- Milk
- Phenotype
- Polymorphism, Single Nucleotide