Article
ApoE and SNAP-25 Polymorphisms Predict the Outcome of Multidimensional Stimulation Therapy Rehabilitation in Alzheimer's Disease.
Neurorehabilitation and neural repair - 1 Oct 2016
Guerini Franca Rosa, Farina Elisabetta, Costa Andrea Saul, Baglio Francesca, Saibene Francesca Lea, Margaritella Nicolò, Calabrese Elena, Zanzottera Milena, Bolognesi Elisabetta, Nemni Raffaello, Clerici Mario
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) is a highly prevalent neurodegenerative disorder. Rate of decline and functional restoration in AD greatly depend on the capacity for neural plasticity within residual neural tissues; this is at least partially influenced by polymorphisms in genes that determine neural plasticity, including Apolipoprotein E4 (ApoE4) and synaptosomal-associated protein of 25 kDa (SNAP-25)....
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