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Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats

17 Mar 2023

Abstract excerpt

BACKGROUNDS: Kidney stone also known as urolithiasis or nephrolithiasis, is one of the oldest diseases known to medicine, however, the gene expression changes and related kidney injury remains unclear. METHODS: A calculi rat model was developed via ethylene glycol- and ammonium chloride-induction. Integrated proteomic and transcriptomic analysis was performed to characterize the distinct gene expression profiles...

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Share to Chronic Kidney Disease and Diabetes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36932340
DOI: 10.1186/s12864-023-09222-7

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