Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A role for CCR5(+)CD4 T cells in cutaneous psoriasis and for CD103(+) CCR4(+) CD8 Teff cells in the associated systemic inflammation.

Journal of autoimmunity - 1 Jun 2016

Sgambelluri Francesco, Diani Marco, Altomare Andrea, Frigerio Elena, Drago Lorenzo, Granucci Francesca, Banfi Giuseppe, Altomare Gianfranco, Reali Eva

Abstract excerpt

Recent results have identified critical components of the T cell response involved in the initiation and amplification phases of psoriasis. However the link between T cell responses arising in the skin and the systemic inflammation associated with severe psoriasis is largely unknown. We hypothesized that specific subsets of memory T cells recirculating from the skin could play a role. We therefore dissected the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD8-Positive T-Lymphocytes
Share to Combined Modality Therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunologic Memory

Share to Integrin alpha Chains

Share to Lymphocyte Count

Share to Psoriasis

Share to Receptors, CCR5

Share to T-Lymphocyte Subsets

Source

Identifiers

PMID: 27068801
DOI: 10.1016/j.jaut.2016.03.019

Genes

CCR5
CCR4
CCL5
CRP
CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A role for CCR5(+)CD4 T cells in cutaneous psoriasis and for CD103(+) CCR4(+) CD8 Teff cells in the associated systemic inflammation.PMID 27068801Read ↗

Skin-Resident Memory T Cells: Pathogenesis and Implication for the Treatment of PsoriasisSemantic proximity Read ↗

Tissue-resident memory T cells in the skin.Semantic proximity Read ↗

T Helper Cell Subsets in Clinical Manifestations of Psoriasis.Semantic proximity Read ↗

Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8 + T Cell ClonesSemantic proximity Read ↗

Single-cell Landscape of Immune Cells in Blood and Skin in PsoriasisSemantic proximity Read ↗

Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3intCD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies.Semantic proximity Read ↗

Clonal sharing of CD8+ T-cells links skin and joint inflammation in psoriatic arthritisSemantic proximity Read ↗

Cd8αα+T Cells Exert a Pro-inflammatory Role in Patients With Psoriasis Semantic proximity Read ↗

Circulating CD8 T cells from patients with mild-to-moderate psoriasis are functionally impairedSemantic proximity Read ↗

The vast majority of CLA+ T cells are resident in normal skin.Semantic proximity Read ↗

The Translational Relevance of Human Circulating Memory Cutaneous Lymphocyte-Associated Antigen Positive T Cells in Inflammatory Skin Disorders.Semantic proximity Read ↗

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.