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Article

CNTF protects neurons from hypoxic injury through the activation of STAT3pTyr705.

International journal of molecular medicine - 1 Dec 2016

Gu Ying Li, Gao Guan Qun, Ma Ning, Ye Lin Lin, Zhang Li Wei, Gao Xu, Zhang Zhuo Bo

Abstract excerpt

The aim of the present study was to investigate whether ciliary neurotrophic factor (CNTF) plays its neuroprotective role following hypoxic injury through the activation of signal transducer and activator of transcription 3 (STAT3) signaling. Firstly, to determine whether CNTF exerts its effects via STAT3 following hypoxic injury, cultured neurons from the cerebral cortex of mice were prepared and a neuronal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27748830
DOI: 10.3892/ijmm.2016.2769

Genes

CNTF
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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