Article
Effector memory CD4(+) T cells differentially express activation associated molecules depending on the duration of American cutaneous leishmaniasis lesions.
Clinical and experimental immunology - 1 Aug 2016
de Oliveira Mendes-Aguiar C, Vieira-Gonçalves R, Guimarães L H, de Oliveira-Neto M P, Carvalho E M, Da-Cruz A M
Abstract excerpt
A high number of Leishmania-responder T cells is found in cutaneous leishmaniasis lesions, suggesting that important immunological events occur at the site of infection. Although activated, cytotoxic and regulatory T cells infiltrating into lesions may influence disease pathogenesis, the role of the T cell differentiation pattern of lymphocytes in lesions is unknown. Our aim was to investigate whether the phase...
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