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The Role of CD4 and CD8â€‰T Cells in Human Cutaneous Leishmaniasis

29 Sept 2014

Abstract excerpt

Leishmaniasis, caused by infection with parasites of the Leishmania genus, affects millions of individuals worldwide. This disease displays distinct clinical manifestations ranging from self-healing skin lesions to severe tissue damage. The control of Leishmania infection is dependent on cellular immune mechanisms, and evidence has shown that CD4 and CD8 T lymphocytes play different roles in the outcome of...

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PMID: 25325049
DOI: 10.3389/fpubh.2014.00165

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