Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intralesional gene expression profile of JAK-STAT signaling pathway and associated cytokines in Leishmania tropica-infected patients

19 Sept 2024

Abstract excerpt

Background The JAK-STAT signaling pathway is a central cascade of signal transduction for the myriad of cytokines in which dysregulation has been implicated in progression of inflammatory and infectious diseases. However, the involvement of this pathway in human cutaneous leishmaniasis (CL) due to Leishmania (L.) tropica warrants further investigation. Methods This study sought to investigate differential gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Research on Leishmaniasis Studies
Share to Synthesis and biological activity
Share to Urticaria and Related Conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39364404
DOI: 10.3389/fimmu.2024.1436029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intralesional gene expression profile of JAK-STAT signaling pathway and associated cytokines in Leishmania tropica-infected patientsPMID 39364404Read ↗

Immune Responses in Leishmaniasis: An OverviewSemantic proximity Read ↗

Potential Therapeutic Targets for Leishmaniasis: Modulating Cytokine Production and ECM OrganizationSemantic proximity Read ↗

Interferon Gamma in LeishmaniasisSemantic proximity Read ↗

Tegumentary Leishmaniasis: Perspectives and Challenges in This Enigmatic DiseaseSemantic proximity Read ↗

Unraveling the Immune Response Dynamics of Leishmaniasis: Insights, Challenges, and Vaccine DevelopmentSemantic proximity Read ↗

STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.Semantic proximity Read ↗

Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signatureSemantic proximity Read ↗

Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progressionSemantic proximity Read ↗

Protective or Detrimental? Understanding the Role of Host Immunity in LeishmaniasisSemantic proximity Read ↗

Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasisSemantic proximity Read ↗

Temporal Expression Dynamics of lncRNAs and Cis-Target Gene Interactions in Leishmania major-Infected Human MacrophagesSemantic proximity Read ↗

Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.