Article
G48A, a New KRAS Mutation Found in Lung Adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2016
Marabese Mirko, Caiola Elisa, Garassino Marina C, Rastelli Giulio, Settanni Giulio, Brugnara Sonia, Broggini Massimo, Ganzinelli Monica
Abstract excerpt
A new somatic mutation in the coding region of Kirsten rat sarcoma viral oncogene homolog gene (KRAS), G48A, has been identified in a patient with non-small cell lung cancer (NSCLC). No other mutations were found by screening several genes known to be mutated in NSCLC. The patient responded to first-line therapy and is still under maintenance treatment 18 months after diagnosis. Normal and cancer cells were...
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