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Article

Reduced non-switched memory B cell subsets cause imbalance in B cell repertoire in systemic sclerosis.

Clinical and experimental rheumatology - 1 Jan 2000

Simon Diána, Balogh Péter, Bognár András, Kellermayer Zoltán, Engelmann Péter, Németh Péter, Farkas Nelli, Minier Tünde, Lóránd Veronika, Czirják László, Berki Tímea

Abstract excerpt

OBJECTIVES: Analysis of peripheral blood B lymphocytes in patients with systemic sclerosis (SSc) has provided evidence for specific alterations in naive and memory B cell balance. However, memory B cell subsets in SSc have not been thoroughly investigated. This study sought to identify phenotypic abnormalities and activation markers in peripheral blood memory B cells in SSc subtypes. METHODS: Blood samples were...

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PMID: 27056741

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