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Article

Generation and Characterization of an Immortalized Human Esophageal Myofibroblast Line.

PloS one - 1 Jan 2016

Niu Chao, Chauhan Uday, Gargus Matthew, Shaker Anisa

Abstract excerpt

Stromal cells with a myofibroblast phenotype present in the normal human esophagus are increased in individuals with gastro-esophageal reflux disease (GERD). We have previously demonstrated that myofibroblasts stimulated with acid and TLR4 agonists increase IL-6 and IL-8 secretion using primary cultures of myofibroblasts established from normal human esophagus. While primary cultures have the advantage of...

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Source

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Identifiers

PMID: 27055018
DOI: 10.1371/journal.pone.0153185
PMCID: PMC4824353

Genes

TLR4
TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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