Article
Limited artemisinin resistance-associated polymorphisms in Plasmodium falciparum K13-propeller and PfATPase6 gene isolated from Bioko Island, Equatorial Guinea.
International journal for parasitology. Drugs and drug resistance - 1 Apr 2016
Li Jian, Chen Jiangtao, Xie Dongde, Eyi Urbano Monsuy, Matesa Rocio Apicante, Ondo Obono Maximo Miko, Ehapo Carlos Sala, Yang Liye, Yang Huitian, Lin Min
Abstract excerpt
OBJECTIVE: With emergence and geographically expanding of antimalarial resistance worldwide, molecular markers are essential tool for surveillance of resistant Plasmodium parasites. Recently, single-nucleotide polymorphisms (SNPs) in the PF3D7_1343700 kelch propeller (K13-propeller) domain are shown to be associated with artemisinin (ART) resistance in vivo and in vitro. This study aims to investigate the ART...
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