Article
Genomic ancestry evaluated by ancestry-informative markers in patients with sickle cell disease.
Genetics and molecular research : GMR - 31 Mar 2016
Nascimento A F, Oliveira J S, Silva Junior J C, Barbosa A A L
Abstract excerpt
The β(s) mutation is responsible for the most aggressive form of sickle cell disease, has a predominantly African origin, and arrived in Brazil through the slave trade. However, the Brazilian population is highly miscegenated, underscoring the importance of ancestry-informative markers (AIMs) for the identification of the genetic structure of a population. In this study, we have estimated the genetic...
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