Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human leukocyte antigen distribution and genomic ancestry in Brazilian patients with sickle cell disease.

HLA - 1 Oct 2017

da Silva-Malta M C F, Rodrigues P S, Zuccherato L W, de Souza F C B, Domingues E M F L, Souza V R, Tarazona-Santos E, Martins M L

Abstract excerpt

Hematopoietic stem-cell transplantation (HSCT) is currently the only established curative treatment for sickle cell disease (SCD), but is limited by donor availability. Ethnicity is thought to have an impact on the complications experienced by patients that undergo HSCT and on the likelihood of identifying an human leukocyte antigen (HLA) matched donor. In the present study, we investigated the genomic ancestry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Black People

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Donor Selection

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Phylogeography

Share to Transplantation, Homologous

Share to Unrelated Donors

Source

Identifiers

PMID: 28731588
DOI: 10.1111/tan.13102

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human leukocyte antigen distribution and genomic ancestry in Brazilian patients with sickle cell disease.PMID 28731588Read ↗

How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians.Semantic proximity Read ↗

Clinical and genetic ancestry profile of a large multi-centre sickle cell disease cohort in Brazil.Semantic proximity Read ↗

An Analysis of Racial and Ethnic Backgrounds Within the CASiRe International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research.Semantic proximity Read ↗

Genetic diversity among volunteer donors of bone marrow in southeastern Brazil, according to the HLA system.Semantic proximity Read ↗

The heterogeneous HLA genetic composition of the Brazilian population and its relevance to the optimization of hematopoietic stem cell donor recruitment.Semantic proximity Read ↗

The distribution of HLA haplotypes in the ethnic groups that make up the Brazilian Bone Marrow Volunteer Donor Registry (REDOME).Semantic proximity Read ↗

Genomic ancestry evaluated by ancestry-informative markers in patients with sickle cell disease.Semantic proximity Read ↗

RHCE diversity among Brazilian patients with sickle cell disease (SCD) and selected groups of blood donors.Semantic proximity Read ↗

Red Blood Cell Alloimmunization in Sickle Cell Disease: Listen to Your AncestorsSemantic proximity Read ↗

ABO and Rh blood group genotypes in a cohort of Saudi stem cell donors.Semantic proximity Read ↗

HLA Allele and Haplotype Frequencies Among Registered Unrelated Donors in the Western Region of Saudi Arabia.Semantic proximity Read ↗

Listing of common HLA alleles and haplotypes based on the study of 356 families residing in the Paris, France, area: implications for unrelated hematopoietic stem cell donor selection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.