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Article

Ancestry Informative Marker Panel to Estimate Population Stratification Using Genome-wide Human Array.

Annals of human genetics - 1 Nov 2017

Barbosa Fernanda B, Cagnin Natalia F, Simioni Milena, Farias Allysson A, Torres Fábio R, Molck Miriam C, Araujo Tânia K, Gil-Da-Silva-Lopes Vera L, Donadi Eduardo A, Simões Aguinaldo L

Abstract excerpt

Case-control studies are a powerful strategy to identify candidate genes in complex diseases. In admixed populations, association studies can be affected by population stratification, leading to spurious genetic associations. Ancestry informative markers (AIMs) can be used to minimise this effect. The aim of this work was to select a set of AIMs to estimate population stratification in a Brazilian case-control...

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PMID: 28895130
DOI: 10.1111/ahg.12208

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