Increased Risk of Psoriasis due to combined effect of HLA-Cw6 and LCE3 risk alleles in Indian population.

doi:10.1038/srep24059

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Increased Risk of Psoriasis due to combined effect of HLA-Cw6 and LCE3 risk alleles in Indian population.

Scientific reports - 6 Apr 2016

Chandra Aditi, Lahiri Anirudhya, Senapati Swapan, Basu Baidehi, Ghosh Saurabh, Mukhopadhyay Indranil, Behra Akhilesh, Sarkar Somenath, Chatterjee Gobinda, Chatterjee Raghunath

Abstract excerpt

HLA-Cw6 is one of the most associated alleles in psoriasis. Recently, Late Cornified Envelop 3 (LCE3) genes were identified as a susceptibility factor for psoriasis. Some population showed epistatic interaction of LCE3 risk variants with HLA-Cw6, while some population failed to show any association. We determined the associations of a 32.2 kb deletion comprising LCE3C-3B genes and three SNPs (rs1886734,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Gene Deletion

Share to HLA-C Antigens

Source

Open in PubMed Open full text

Identifiers

PMID: 27048876
DOI: 10.1038/srep24059
PMCID: PMC4822143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased Risk of Psoriasis due to combined effect of HLA-Cw6 and LCE3 risk alleles in Indian population.PMID 27048876Read ↗

Association of the late cornified envelope-3 genes with psoriasis and psoriatic arthritis: a systematic review.Semantic proximity Read ↗

Functional Mapping of Genetic Interactions between HLA-Cw6 and LCE3A in Psoriasis.Semantic proximity Read ↗

Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.Semantic proximity Read ↗

Deletion of the late cornified envelope genes LCE3C and LCE3B is associated with psoriasis in a Chinese population.Semantic proximity Read ↗

Deletion of LCE3C and LCE3B genes is associated with psoriasis in a northern Chinese population.Semantic proximity Read ↗

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis.Semantic proximity Read ↗

Psoriasis Risk Genes of the Late Cornified Envelope-3 Group Are Distinctly Expressed Compared with Genes of Other LCE GroupsSemantic proximity Read ↗

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.Semantic proximity Read ↗

[Enlightenment from genome-wide association study to genetics of psoriasis].Semantic proximity Read ↗

Psoriasis: An Immunogenetic PerspectiveSemantic proximity Read ↗

Genetics of psoriasis: a basis for precision medicineSemantic proximity Read ↗

Pushing the Envelope in Psoriasis: Late Cornified Envelope Proteins Possess Antimicrobial Activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.