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Article

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

5 Apr 2016

Abstract excerpt

BACKGROUND: Glaucoma is a complex, multifactorial disease characterised by the loss of retinal ganglion cells and their axons leading to a decrease in visual function. The earliest events that damage retinal ganglion cells in glaucoma are currently unknown. Retinal ganglion cell death appears to be compartmentalised, with soma, dendrite and axon changes potentially occurring through different mechanisms. There is...

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PMID: 27048300
DOI: 10.1186/s13024-016-0091-6

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