Interallelic interaction and gene regulation in budding yeast.

doi:10.1073/pnas.1601003113

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Article

Interallelic interaction and gene regulation in budding yeast.

Proceedings of the National Academy of Sciences of the United States of America - 19 Apr 2016

Zhang Daoyong, Bai Lu

Abstract excerpt

InDrosophila, homologous chromosome pairing leads to "transvection," in which the enhancer of a gene can regulate the allelic transcription intrans.Interallelic interactions were also observed in vegetative diploid budding yeast, but their functional significance is unknown. Here, we show that aGAL1reporter can interact with its homologous allele and affect its expression. By ectopically inserting two allelic...

Topics

Alleles
Galactokinase
Gene Expression Regulation, Fungal
Mutation
Promoter Regions, Genetic
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transcription, Genetic

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Identifiers

PMID: 27044105
DOI: 10.1073/pnas.1601003113
PMCID: PMC4843442

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