Article
Implantation of a Novel Allogeneic Mesenchymal Precursor Cell Type in Patients with Ischemic Cardiomyopathy Undergoing Coronary Artery Bypass Grafting: an Open Label Phase IIa Trial.
Journal of cardiovascular translational research - 1 Jun 2016
Anastasiadis Kyriakos, Antonitsis Polychronis, Westaby Stephen, Reginald Ajan, Sultan Sabena, Doumas Argirios, Efthimiadis George, Evans Martin John
Abstract excerpt
Heart failure is a life-limiting condition affecting over 40 million patients worldwide. Ischemic cardiomyopathy (ICM) is the most common cause. This study investigates in situ cardiac regeneration utilizing precision delivery of a novel mesenchymal precursor cell type (iMP) during coronary artery bypass surgery (CABG) in patients with ischemic cardiomyopathy (LVEF < 40 %). The phase IIa safety study was designed...
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