Article
Autologous stem cell transplantation for myocardial repair.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2004
Liu Jingbo, Hu Qingsong, Wang Zongli, Xu Chengsu, Wang Xiaohong, Gong Guangrong, Mansoor Abdul, Lee Joseph, Hou Mingxiao, Zeng Lepeng, Zhang John R, Jerosch-Herold Michael, Guo Tao, Bache Robert J, Zhang Jianyi
Abstract excerpt
Current therapies for heart failure due to transmural left ventricular (LV) infarction are limited. We have developed a novel patch method for delivering autologous bone marrow stem cells to sites of myocardial infarction for the purpose of improving LV function and preventing LV aneurysm formation. The patch consisted of a fibrin matrix seeded with autologous porcine mesenchymal stem cells labeled with lacZ. We...
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