HLA-DRB1*03 as a risk factor for microalbuminuria in same duration of type 1 diabetes: a case control study.

doi:10.1186/s12882-016-0252-4

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Article

HLA-DRB1*03 as a risk factor for microalbuminuria in same duration of type 1 diabetes: a case control study.

BMC nephrology - 31 Mar 2016

Ražanskaitė-Virbickienė Dovilė, Danytė Evalda, Žalinkevičius Rimantas

Abstract excerpt

BACKGROUND: Increased urinary albumin excretion rate is the earliest clinical manifestation of diabetic nephropathy. The development of microalbuminuria in patients with type 1 diabetes mellitus (T1D) usually begins 5 to 15 years after the onset of diabetes. The rate of progression of diabetic nephropathy varies considerably among patients and not always can be explained solely by glycaemic control. The evidence...

Topics

Adult
Albuminuria
Case-Control Studies
Diabetes Mellitus, Type 1
Female
Genetic Predisposition to Disease
Genotype
HLA-DRB1 Chains
Humans
Male
Young Adult

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Identifiers

PMID: 27036319
DOI: 10.1186/s12882-016-0252-4
PMCID: PMC4815109

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