Article
Combined Administration of ASCs and BMP-12 Promotes an M2 Macrophage Phenotype and Enhances Tendon Healing.
Clinical orthopaedics and related research - 1 Sept 2017
Gelberman Richard H, Linderman Stephen W, Jayaram Rohith, Dikina Anna D, Sakiyama-Elbert Shelly, Alsberg Eben, Thomopoulos Stavros, Shen Hua
Abstract excerpt
BACKGROUND: Outcomes after intrasynovial tendon repair are highly variable. An intense inflammatory cascade followed by a delayed healing response can cause adhesion formation and repair-site failure that severely impair the function of repaired digits. No effective remedies exist to fully address these issues. Cell- and growth factor-based therapies have been shown to modulate inflammation and improve cell...
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