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Article

Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal region.

Experimental eye research - 1 Aug 2002

Muller-Weeks Susan, Boesze-Battaglia Kathleen, Fitzgerald Catherine

Abstract excerpt

The C-terminal region of peripherin/rds contains three predicted alpha-helical domains. One of these domains, corresponding to amino acids 311-322, form an amphiphilic alpha-helix previously shown to promote membrane fusion. The present studies were conducted to determine how the additional alpha-helical regions of the peripherin/rds C-terminus affect complex formation with rom-1, glycosylation, intracellular...

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Source

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Identifiers

PMID: 12137760
DOI: 10.1006/exer.2002.2013
PMCID: PMC4746731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal region.PMID 12137760Read ↗

A soluble peripherin/Rds C-terminal polypeptide promotes membrane fusion and changes conformation upon membrane association.Semantic proximity Read ↗

Peripherin/rds Influences Membrane Vesicle MorphologySemantic proximity Read ↗

Expression and characterization of peripherin/rds-rom-1 complexes and mutants implicated in retinal degenerative diseases.Semantic proximity Read ↗

Role of the Second Intradiscal Loop of Peripherin/<i>rds </i>in Homo and Hetero AssociationsSemantic proximity Read ↗

Transgenic analysis of rds/peripherin N-glycosylation: effect on dimerization, interaction with rom1, and rescue of the rds null phenotype.Semantic proximity Read ↗

An intramembrane glutamic acid governs peripherin/rds function for photoreceptor disk morphogenesis.Semantic proximity Read ↗

An inducible amphipathic helix within the intrinsically disordered C terminus can participate in membrane curvature generation by peripherin-2/rds.Semantic proximity Read ↗

The Role of Peripherin-2/ROM1 Complexes in Photoreceptor Outer Segment Disc Morphogenesis.Semantic proximity Read ↗

Analysis of the rds/peripherin.rom1 complex in transgenic photoreceptors that express a chimeric protein.Semantic proximity Read ↗

Role of peripherin/rds in vertebrate photoreceptor architecture and inherited retinal degenerations.Semantic proximity Read ↗

The spectrum of retinal dystrophies caused by mutations in the peripherin/RDS gene.Semantic proximity Read ↗

Folding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: implications for heterogeneous molecular pathologies.Semantic proximity Read ↗

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