Role of peripherin/rds in vertebrate photoreceptor architecture and inherited retinal degenerations.

doi:10.1016/S0074-7696(06)53004-9

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Article

Role of peripherin/rds in vertebrate photoreceptor architecture and inherited retinal degenerations.

International review of cytology - 1 Jan 2006

Goldberg Andrew F X

Abstract excerpt

The vertebrate photoreceptor outer segment (OS) is a highly structured and dynamic organelle specialized to transduce light signals. The elaborate membranous architecture of the OS requires peripherin/rds (P/rds), an integral membrane protein and tetraspanin protein family member. Gene-level defects in P/rds cause a broad variety of late-onset progressive retinal degenerations in humans and dysmorphic...

Topics

Amino Acid Sequence
Animals
Humans
Intermediate Filament Proteins
Intracellular Membranes
Membrane Glycoproteins
Membrane Proteins
Mice
Models, Anatomic
Models, Biological
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nerve Tissue Proteins

Peripherins

Photoreceptor Cells, Vertebrate

Retinal Degeneration

Sequence Homology, Amino Acid

Xenopus Proteins

Source

Open in PubMed

Identifiers

PMID: 17098056
DOI: 10.1016/S0074-7696(06)53004-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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