Article
Genomewide linkage scan for combined obesity phenotypes using principal component analysis.
Annals of human genetics - 1 May 2008
He L-N, Liu Y-J, Xiao P, Zhang L, Guo Y, Yang T-L, Zhao L-J, Drees B, Hamilton J, Deng H-Y, Recker R R, Deng H-W
Abstract excerpt
Traditional whole genome linkage scans for obesity were usually performed for a number of correlated obesity related phenotypes separately without considering their correlations. The purpose of this study was to identify quantitative trait loci (QTLs) underlying variations in multiple correlated obesity phenotypes. We performed principal component analysis (PCA) for four highly correlated obesity phenotypes (body...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.