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Article

Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes

9 Jan 2014

Abstract excerpt

Pluripotent stem cells (PSCs) represent an appealing source from which to develop cell replacement therapies. Different initiatives have been launched to promote their development toward clinical applications. This article will review the main questions that should be considered before translating PSC-derived cardiomyocytes into clinical investigations, including the development of good manufacturing...

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PMID: 24405778
DOI: 10.1186/scrt390

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