Article
Possible biomarkers modulating haloperidol efficacy and/or tolerability.
Pharmacogenomics - 1 Apr 2016
Porcelli Stefano, Crisafulli Concetta, Calabrò Marco, Serretti Alessandro, Rujescu Dan
Abstract excerpt
Haloperidol (HP) is widely used in the treatment of several forms of psychosis. Despite of its efficacy, HP use is a cause of concern for the elevated risk of adverse drug reactions. adverse drug reactions risk and HP efficacy greatly vary across subjects, indicating the involvement of several factors in HP mechanism of action. The use of biomarkers that could monitor or even predict HP treatment impact would be...
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