Article
Generation and Application of Male Mice with Specific Expression of Green Fluorescent Protein in Germ Cells.
Molecular imaging and biology - 1 Oct 2016
Wang Zhiru, Li Jun, Cao Dong, Liu Xiaomei, Zhu Desheng
Abstract excerpt
PURPOSE: The study aimed to generate a mouse line with green fluorescent protein (GFP) specifically expressed in male germ cells to assess testicular toxicity. PROCEDURES: The mouse line with GFP specifically expressed in male germ cells was generated by mating a germ cell-specific transgenic Cre male mouse with a double-fluorescent reporter female mouse using Cre/loxP. The mouse line was administered ethylene...
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