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Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice

23 Dec 2015

Abstract excerpt

Fetal and adult Leydig cells develop in mammalian prenatal and postnatal testes, respectively. In mice, fetal Leydig cells (FLCs) emerge in the interstitial space of the testis at embryonic day 12.5 and thereafter increase in number, possibly through differentiation from progenitor cells. However, the progenitor cells have not yet been identified. Previously, we established transgenic mice in which FLCs are...

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PMID: 26697723
DOI: 10.1210/en.2015-1773

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