Article
XPG gene polymorphisms and glioma susceptibility: a two-centre case-control study.
British journal of biomedical science - 1 Jul 2021
Yuan L, Hu W M, Chen K, Shi Q, Lin A, Chen H T, Zhuo Z J, Zeng L
Abstract excerpt
Background: Glioma, the most common tumour in children next to leukaemia, is difficult to treat, with a poor prognosis and high recurrence rate. Xeroderma pigmentosum group G (XPG) plays a key role in the nucleotide excision repair pathway, which may modulate individual susceptibility to developing cancer. We hypothesized links between XPG variants and glioma in children.Methods: We tested our hypothesis in a...
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