Article
XPG rs873601 G>A contributes to uterine leiomyoma susceptibility in a Southern Chinese population.
Bioscience reports - 31 Oct 2018
Liu Zhi-Qin, Chen Guan-Ge, Sun Ru-Liang, Chen Chao, Lu Mei-Yin, Guan Lan-Fang, Chi Xiao-Ling, Jian You-Qiang, Zhu Xiu, Liu Rui-Qi, Cai Bo-Yu, Chen Fang-Fang, Liu Bin
Abstract excerpt
XPG gene contributes to DNA repair defects and genomic instability, which may lead to the initiation of uterine leiomyoma. We hypothesized that genetic variants of XPG gene may alter the carriers' susceptibility to leiomyoma. The association between five potential functional single nucleotide polymorphisms (SNPs), i.e. rs2094258 C>T, rs751402 C>T, rs2296147 T>C, rs1047768 T>C, rs873601 G>A, and uterine leiomyoma...