Article
Clinical and laboratory update on the DEL variant.
Laboratory medicine - 1 Jan 2014
Nuchnoi Pornlada, Thongbus Jairak, Srisarin Apapan, Kerdpin Usanee, Prachayasittikul Virapong
Abstract excerpt
Serological assays for the RhD blood group are based on detection of the RhD antigen on human red blood cells using a specific anti-D antibody. The weak expression of the RhD antigen in the DEL variant hinders the sensitivity of conventional serological assays. Evidence of anti-D immunization in patients with D-negativity who have received DEL-variant blood units has been reported in various populations. This...
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