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Article

PKM1 is involved in resistance to anti-cancer drugs.

Biochemical and biophysical research communications - 22 Apr 2016

Taniguchi Kohei, Sakai Miku, Sugito Nobuhiko, Kuranaga Yuki, Kumazaki Minami, Shinohara Haruka, Ueda Hiroshi, Futamura Manabu, Yoshida Kazuhiro, Uchiyama Kazuhisa, Akao Yukihiro

Abstract excerpt

Resistance to chemotherapy is a crucial problem in the clinical situation. To overcome this issue, many mechanisms of chemoresistance have been elucidated so far. However, this problem still has not been solved completely. In this study, we investigated the mechanism of chemoresistance from the view of cancer metabolism-related genes, especially focusing on the expression profile of pyruvate kinase muscle (PKM)...

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PMID: 27012213
DOI: 10.1016/j.bbrc.2016.03.074

Genes

DLD
PKM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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