Article
A Method for Amplicon Deep Sequencing of Drug Resistance Genes in Plasmodium falciparum Clinical Isolates from India.
Journal of clinical microbiology - 1 Jun 2016
Rao Pavitra N, Uplekar Swapna, Kayal Sriti, Mallick Prashant K, Bandyopadhyay Nabamita, Kale Sonal, Singh Om P, Mohanty Akshaya, Mohanty Sanjib, Wassmer Samuel C, Carlton Jane M
Abstract excerpt
A major challenge to global malaria control and elimination is early detection and containment of emerging drug resistance. Next-generation sequencing (NGS) methods provide the resolution, scalability, and sensitivity required for high-throughput surveillance of molecular markers of drug resistance. We have developed an amplicon sequencing method on the Ion Torrent PGM platform for targeted resequencing of a...
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