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Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro

1 Mar 2016

Abstract excerpt

Mesenchymal stem cells (MSCs) are known for their important properties involving multilineage differentiation potential., trophic factor secretion and localization along various organs and tissues. On the dark side, MSCs play a distinguished role in tumor microenvironments by differentiating into tumor-associated fibroblasts or supporting tumor growth via distinct mechanisms. Cisplatin (CIS) is a drug widely...

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PMID: 27007906
DOI: 10.1590/1678-4685-gmb-2015-0057

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