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Article

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome.

Nature microbiology - 1 Mar 2018

Schirmer Melanie, Franzosa Eric A, Lloyd-Price Jason, McIver Lauren J, Schwager Randall, Poon Tiffany W, Ananthakrishnan Ashwin N, Andrews Elizabeth, Barron Gildardo, Lake Kathleen, Prasad Mahadev, Sauk Jenny, Stevens Betsy, Wilson Robin G, Braun Jonathan, Denson Lee A, Kugathasan Subra, McGovern Dermot P B, Vlamakis Hera, Xavier Ramnik J, Huttenhower Curtis

Abstract excerpt

Inflammatory bowel disease (IBD) is a group of chronic diseases of the digestive tract that affects millions of people worldwide. Genetic, environmental and microbial factors have been implicated in the onset and exacerbation of IBD. However, the mechanisms associating gut microbial dysbioses and aberrant immune responses remain largely unknown. The integrative Human Microbiome Project seeks to close these gaps...

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Identifiers

PMID: 29311644
DOI: 10.1038/s41564-017-0089-z
PMCID: PMC6131705

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