Article
Y98 Mutation Leads to the Loss of RsfS Anti-Association Activity in Staphylococcus aureus.
International journal of molecular sciences - 18 Sept 2022
Fatkhullin Bulat, Golubev Alexander, Garaeva Natalia, Validov Shamil, Gabdulkhakov Azat, Yusupov Marat
Abstract excerpt
Ribosomal silencing factor S (RsfS) is a conserved protein that plays a role in the mechanisms of ribosome shutdown and cell survival during starvation. Recent studies demonstrated the involvement of RsfS in the biogenesis of the large ribosomal subunit. RsfS binds to the uL14 ribosomal protein on the large ribosomal subunit and prevents its association with the small subunit. Here, we estimated the contribution...
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