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Article

Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration.

Stem cells (Dayton, Ohio) - 1 Jun 2016

Ohlemacher Sarah K, Sridhar Akshayalakshmi, Xiao Yucheng, Hochstetler Alexandra E, Sarfarazi Mansoor, Cummins Theodore R, Meyer Jason S

Abstract excerpt

Human pluripotent stem cells (hPSCs), including both embryonic and induced pluripotent stem cells, possess the unique ability to readily differentiate into any cell type of the body, including cells of the retina. Although previous studies have demonstrated the ability to differentiate hPSCs to a retinal lineage, the ability to derive retinal ganglion cells (RGCs) from hPSCs has been complicated by the lack of...

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Identifiers

PMID: 26996528
DOI: 10.1002/stem.2356
PMCID: PMC4892962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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