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Article

JAG1 and COL1A1 polymorphisms and haplotypes in relation to bone mineral density variations in postmenopausal Mexican-Mestizo Women.

Age (Dordrecht, Netherlands) - 1 Apr 2013

Rojano-Mejía David, Coral-Vázquez Ramón M, Espinosa Leticia Cortes, López-Medina Guillermo, Aguirre-García María C, Coronel Agustín, Canto Patricia

Abstract excerpt

Osteoporosis is characterized by low bone mineral density (BMD). One of the most important factors that influence BMD is the genetic contribution. The collagen type 1 alpha 1 (COL1A1) and the JAGGED (JAG1) have been investigated in relation to BMD. The aim of this study was to investigate the possible association between two single-nucleotide polymorphisms (SNPs) of COL1A1, their haplotypes, and one SNP of JAG1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22174012
DOI: 10.1007/s11357-011-9363-9
PMCID: PMC3592947

Genes

JAG1

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